Au-SN Flip-Chip Solder Bump for Microelectronic and Optoelectronic Applications

As an alternative to the time-consuming solder pre-forms and pastes currently used, a co-electroplating method of eutectic Au-Sn alloy was used in this study. Using a co-electroplating process, it was possible to plate the Au-Sn solder directly onto a wafer at or near the eutectic composition from a single solution. Two distinct phases, Au5Sn and AuSn, were deposited at a composition of 30at.%Sn. The Au-Sn flip-chip joints were formed at 300 and 400 degrees without using any flux. In the case where the samples were reflowed at 300 degrees, only an (Au,Ni)3Sn2 IMC layer formed at the interface between the Au-Sn solder and Ni UBM. On the other hand, two IMC layers, (Au,Ni)3Sn2 and (Au,Ni)3Sn, were found at the interfaces of the samples reflowed at 400 degrees. As the reflow time increased, the thickness of the (Au,Ni)3Sn2 and (Au,Ni)3Sn IMC layers formed at the interface increased and the eutectic lamellae in the bulk solder coarsened.Comment: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions

Diagnostic performance of the 2022 KLCA-NCC criteria for hepatocellular carcinoma on magnetic resonance imaging with extracellular contrast and hepatobiliary agents: comparison with the 2018 KLCA-NCC criteria

Background/Aim This study aimed to determine the diagnostic performance of 2022 Korean Liver Cancer Association-National Cancer Center (KLCA-NCC) imaging criteria compared with the 2018 KLCA-NCC for hepatocellular carcinoma (HCC) in high-risk patients using magnetic resonance imaging (MRI). Methods This retrospective study included 415 treatment-naïve patients (152 patients who underwent extracellular contrast agent [ECA]-MRI and 263 who underwent hepatobiliary agent [HBA]-MRI; 535 lesions, including 412 HCCs) with a high risk of HCC who underwent contrast-enhanced MRI. Two readers evaluated all lesions according to the 2018 and 2022 KLCA-NCC imaging diagnostic criteria, and the per-lesion diagnostic performances were compared. Results In “definite” HCC category of both 2018 and 2022 KLCA-NCC, HBA-MRI showed a significantly higher sensitivity for the diagnosis of HCC than ECA-MRI (77.0% vs. 64.3%, P=0.006) without a significant difference in specificity (94.7% vs. 95.7%, P=0.801). On ECAMRI, “definite” or “probable” HCC categories of the 2022 KLCA-NCC had significantly higher sensitivity than those of the 2018 KLCA-NCC (85.3% vs. 78.3%, P=0.002) with identical specificity (93.6%). On HBA-MRI, the sensitivity and specificity of “definite” or “probable” HCC categories of both 2018 and 2022 KLCA-NCC were not significantly different (83.3% vs. 83.6%, P>0.999 and 92.1% vs. 90.8%, P>0.999, respectively). Conclusions In “definite” HCC category of both 2018 and 2022 KLCA-NCC, HBA-MRI provides better sensitivity than ECA-MRI without compromising specificity. On ECA-MRI, “definite” or “probable” HCC categories of the 2022 KLCA-NCC may improve sensitivity in the diagnosis of HCC compared with the 2018 KLCA-NCC

ETSI SmartM2M Technical Report 103714: Study for oneM2M Discovery and Query use cases and requirements

The oneM2M system has implemented basic native discovery capabilities. In order to enhance the semantic capabilities of the oneM2M architecture by providing solid contributions to the oneM2M standards, four Technical Reports have been developed. Each of them is the outcome of a special study phase: requirements, study, simulation and standardization phase. The present document covers the first phase and provides the basis for the other documents.The use cases specified in the present document lead to potential requirements, which extend the existing requirements of the use case documented in oneM2M TR-0001 [i.19], clause 12.9 with a focus on the discovery and query capabilities, introducing a direct relation with the semantic aspects and enabling more sophisticated semantic queries as e.g. a capability in the CSE, that takes routing decisions for forwarding a received Advanced Semantic Discovery Query.oneM2M has currently native discovery capabilities that work properly only if the search is related to specific known sources of information (e.g. searching for the values of a known set of containers) or if the discovery is well scoped and designed (e.g. the lights in a house). When oneM2M is used to discover wide sets of data or unknown sets of data, the functionality is typically integrated by ad hoc applications that are expanding the oneM2M functionality. This means that this core function may be implemented with different flavours and this is not optimal for interworking and interoperability.The objective of the present document [i.1] in conjunction with three other ones [i.2], [i.3] and [i.4] is the study and development of semantic Discovery and Query capabilities for oneM2M and its contribution to the oneM2M standard.The goal is to enable an easy and efficient discovery of information and a proper interworking with external source/consumers of information (e.g. a distributed data base in a smart city or in a firm), or to directly search information in the oneM2M system for big data purposes

Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction

We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute ST-elevation myocardial infarction (STEMI) between November 2005 and December 2006 were categorized according to the National Cholesterol Education Program-Adult Treatment Panel III criteria of MS. Primary study outcomes included major adverse cardiac events (MACE) during one-year follow-up. Patients were grouped based on existence of MS: group I: MS (n=1,182, 777 men, 62.8±12.3 yr); group II: Non-MS (n=808, 675 men, 64.2±13.1 yr). Group I showed lower left ventricular ejection fraction (LVEF) (P=0.005). There were no differences between two groups in the coronary angiographic findings except for multivessel involvement (P=0.01). The incidence of in-hospital death was higher in group I than in group II (P=0.047), but the rates of composite MACE during one-year clinical follow-up showed no significant differences. Multivariate analysis showed that low LVEF, old age, MS, low high density lipoprotein cholesterol and multivessel involvement were associated with high in-hospital death rate. In conclusion, MS is an important predictor for in-hospital death in patients with STEMI

Dietary supplement use by South Korean adults: Data from the national complementary and alternative medicine use survey (NCAMUS) in 2006

There has been little data on the prevalence of supplement use and the characteristics of the dietary supplement users in the Republic of Korea. This study presents the prevalence and the details of any dietary supplement use and the characteristics of the adults who use dietary supplements in the Republic of Korea. Between May 18 and June 16, 2006, nationwide and population-weighted personal interviews with 6,201 adult aged from 30 to 69 years were conducted and the final sample consisted of 3,000 people with a 49.8% response rate. We examined the prevalence and details of the use of dietary supplements and the characteristics of those who use the dietary supplement among adults. About sixty two percent of adults had taken any dietary supplement during the previous 12-month period in 2006. The most commonly reported dietary supplement was ginseng, followed by multivitamins, glucosamine, probiotics, and vitamin C. Female (versus male), an older age group, a higher family income, those living in metropolitan cities, those with marital experience, those with a higher level of education, and those having medical problems had a greater likelihood of reporting the use of any dietary supplements. The particular relationships differed depending on the type of supplement. The most Korean adults took one more dietary supplement and the dietary supplement users had different demographic and health characteristics compared to those of the nonusers. Research on diet supplements by the medical community is needed in the future

ETSI SmartM2M Technical Report 103717; Study for oneM2M; Discovery and Query specification development

The oneM2M system has implemented basic native discovery capabilities. In order to enhance the semantic capabilities of the oneM2M architecture by providing solid contributions to the oneM2M standards, four Technical Reports have been developed. Each of them is the outcome of a special study phase: requirements, study, simulation and standardization phase. The present document covers the second phase and provides the basis for the other documents. It identifies, defines and analyses relevant approaches with respect to the use cases and requirements developed in ETSI TR 103 714 The most appropriate one will be selected.The present document develops the specification for the discovery solution selected in ETSI TR 103 715 [i.2] and which simulation is documented in ETSI TR 103 716 [i.3]. The present document specifies candidate solutions while the corresponding standardization proposals are contributed to oneM2M TS-0001 (Architecture) [i.5], oneM2M TS- 0034 (Semantic support) [i.7], oneM2M TS-0033 (Interworking Framework) [i.18], oneM2M TS-0004 (Protocols) [i.19] (other oneM2M TS may be also impacted) with the help of the supporting companies active in oneM2M